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Unique biodegradable polymer matrix

  • Combination of hydrophilic and hydrophobic polymers in form of thin coating layers on stent
  • Provides control over drug release
  • Ensures excellent coating integrity

Unique blend of hydrophlic-hydrophbic biodegradable polymers to elute everolimus drug (bi-phasic release)

Blend of biodegradable polymers
PLLA: Poly-L-lactide
PLCL: Ploy L-Lactide-co-Caprolactone
PVP: Polyvinyl Pyrrolidone
Strut cross section
Polymer thickness 4 - 6 μm
Tetrilimus (3.00mm x 36mm)
LCX diffused lesion at bifurcation of OM1 with 90 degree bend at the bifurcation of left main
LCX Mid Post Stent TIMI Flow
Drug release profile
  • Drug: Everolimus
  • Drug dose: 1.0 µg/mm2
  • Release kinetics
    • About 80% of drug is released at 4 weeks in biological media while 100% drug is released at a slow rate within 3 months.
    • The initial moderate level of everolimus drug release from middle layer coating helps to inhibit the early phase of neointimal hyperplasia.
    • Controlled drug release kinetics from the base layer is beneficial to maintain the effective amount of drug level in the arterial tissues which are required to prevent smooth muscle cell proliferation.
Cumulative drug release

Tetrilimus is 2 times more flexible than predicate device in crimped state which infers that Tetrilimus has better:

  • Trackability
  • Pushability
  • Conformability

Lowest strut thickness across all the diameters

Compliance chart
Nominal Pressure = 8 atm for 2.00 mm to 2.25 mm, 10 atm for 2.50 mm to 3.00 mm, 11 atm for 3.50 mm to 4.00 mm RBP = 16 atm for all sizes
Size matrix

Tetrilimus is a trademark of Sahajanand Medical Technologies Ltd. or its affiliates. Specifications are subject to modification, revision and improvement.

BioFreedom and BioMatrix Alpha are trademarks of Biosensors International. Xience V, Xience Alpine, Xience Prime, Xience Xpedition and Xience Sierra are trademarks of the Abbott Group of Companies. Resolute Onyx is a trademark of Medtronic, Inc. or it's affiliates. Synergy is a trademark of Boston Scientific Corporation or its affiliates. Ultimaster is a trademark of Terumo Corporation. Orsiro is a trademark of Biotronik SE.

Instructions for use